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Stroke is a leading cause of death and disability in China, affecting 17.8 million adults in 2020. Rising risk factors like diabetes and hypertension contribute to this growing burden, necessitating improved prevention and treatment strategies.

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Area of Science:

  • Public Health
  • Epidemiology
  • Neurology

Background:

  • Stroke is the leading cause of death and disability in China, a significant public health challenge.
  • An estimated 17.8 million adults experienced stroke in China in 2020, with 2.2 million resulting in disability.
  • Aging population and poorly controlled risk factors like hypertension, diabetes, and hyperlipidemia are increasing the stroke burden.

Purpose of the Study:

  • To analyze the epidemiological characteristics, treatment patterns, and outcomes of stroke in China.
  • To provide data-driven insights for the 'Healthy China 2030 Stroke Action Plan'.
  • To inform future stroke prevention and treatment strategies nationwide.

Main Methods:

  • Utilized data from the Bigdata Observatory Platform for Stroke of China (BOSC) and other national surveys.
  • Included data from 1599 hospitals for 2020 stroke admissions and a prospective nationwide study (2019-2020) with 136,282 patients.
  • Analyzed stroke types (ischemic stroke, intracerebral hemorrhage, subarachnoid hemorrhage), treatment interventions (IVT, MT), costs, and patient outcomes (disability, mortality, recurrence).

Main Results:

  • In 2020, 3.4 million first-ever strokes occurred, with an in-hospital death/discharge against medical advice rate of 9.2%.
  • Ischemic stroke (IS) constituted over 80% of cases, with significant variations in hospitalization costs and mortality across stroke types.
  • At 12-month follow-up, stroke survivors had a 14.0% disability rate, 8.5% mortality rate, and 5.6% recurrence rate.

Conclusions:

  • Stroke represents a substantial and growing health burden in China, driven by demographic and lifestyle factors.
  • Current treatment interventions like intravenous thrombolytic therapy and mechanical thrombectomy show varying efficacy and complication rates.
  • The findings underscore the urgent need for enhanced stroke prevention, early detection, and effective management strategies across China.