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Related Concept Videos

IR Frequency Region: X–H Stretching01:24

IR Frequency Region: X–H Stretching

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In IR spectroscopy, signals produced by the X−H bonds (such as C−H, O−H, or N−H) can be observed in the frequency range of  2700–4000 cm–1. The C−H stretching vibration forms sharp bands in the region 2850–3000 cm–1. The presence of the O−H stretching vibration leads to the forming of an absorption band in the frequency range 3650–3200 cm−1. At the same time, N−H stretching can be confirmed by absorption bands in...
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Computed Tomography01:10

Computed Tomography

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Tomography refers to imaging by sections. Computed tomography (CT) is a non-invasive imaging technique that uses computers to analyze several cross-sectional X-rays to reveal minute details about structures in the body.
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Imaging Biological Samples with Optical Microscopy01:18

Imaging Biological Samples with Optical Microscopy

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Optical microscopy uses optic principles to provide detailed images of samples. Antonie van Leeuwenhoek designed the first compound optical microscope in the 17th century to visualize blood cells, bacteria, and yeast cells. In 1830, Joseph Jackson Lister created an essentially modern light microscope. The 20th century saw the development of microscopes with enhanced magnification and resolution.
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Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview01:13

Attenuated Total Reflectance (ATR) Infrared Spectroscopy: Overview

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Attenuated total reflectance (ATR) infrared spectroscopy is a powerful analytical technique used to study the composition of materials. It is widely employed in chemistry, materials science, forensic science, and other fields where sample characterization is required. ATR has several advantages over traditional transmission IR spectroscopy, including the requirement of little to no sample preparation and the ability to analyze a wide range of samples.
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Total Internal Reflection Fluorescence Microscopy01:05

Total Internal Reflection Fluorescence Microscopy

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Total internal reflection fluorescence microscopy or TIRF is an advanced microscopic technique used to visualize fluorophores in samples close to a solid surface with a higher refractive index, such as a glass coverslip. TIRF only allows fluorophores in proximity to the solid surface to be excited. When light from a medium with a lower refractive index (such as air) hits the glass coverslip at a critical angle, the light undergoes total internal reflection stead of passing through the glass.
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UV–Vis Spectroscopy: Woodward–Fieser Rules01:29

UV–Vis Spectroscopy: Woodward–Fieser Rules

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UV–Visible absorption spectra of conjugated dienes arise from the lowest energy π → π* transitions. The light-absorbing part of the molecule is called the chromophore, and the substituents directly attached to the chromophore are called auxochromes. A strong correlation exists between the absorption maxima, λmax, and the structure of a conjugated π system. The Woodward–Fieser rules predict the value of λmax for a given...
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Related Experiment Video

Updated: Jul 22, 2025

Microfluidic Imaging Flow Cytometry by Asymmetric-detection Time-stretch Optical Microscopy ATOM
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Visible wavelength time-stretch optical coherence tomography.

Hossein Asghari

    Optics Express
    |July 21, 2023
    PubMed
    Summary

    A new visible-light photonic time-stretch optical coherence tomography (OCT) system achieves record speeds. This breakthrough in time-stretch OCT imaging enables faster anatomical and functional analysis of biological tissues.

    Area of Science:

    • Biomedical optics
    • Optical imaging
    • Photonics

    Background:

    • Visible light optical coherence tomography (OCT) is a developing non-invasive imaging technique for biological tissues.
    • Photonic time-stretch (PTS) enables real-time Fourier transformation for high-speed OCT.

    Purpose of the Study:

    • To propose and demonstrate a working prototype of a visible-light photonic time-stretch OCT (TS-OCT) system.
    • To expand the applications of TS-OCT by operating in the visible wavelength region.

    Main Methods:

    • Experimental demonstration of a novel visible-light TS-OCT system.
    • Utilizing photonic time-stretch for ultrafast optical signal processing and real-time Fourier transformation.

    Main Results:

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  • Achieved an unprecedented throughput of 100 giga voxels/second.
  • Reached an OCT volume rate of 4,000 volumes/second.
  • Successfully implemented TS-OCT in the visible light spectrum.

    • Conclusions:

    • The developed visible-light TS-OCT system offers significant advancements in imaging speed.
    • This technology has the potential to broaden the scope of TS-OCT applications in biological imaging.