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Updated: Jul 22, 2025

Synthesis of Information-bearing Peptoids and their Sequence-directed Dynamic Covalent Self-assembly
Published on: February 6, 2020
Enantioselective resolution of two model amino acids using inherently chiral oligomer films with uncorrelated
Thitapond Nulek1, Serena Arnaboldi2, Gerardo Salinas3
1Department of Chemical and Biomolecular Engineering, School of Energy Science and Engineering, Vidyasirimedhi Institute of Science and Technology, 555 Moo 1, Payupnai, Wang Chan, Rayong 21210, Thailand. adrian.flood@vistec.ac.th.
Abstract:
Preferential crystallization induced by chiral surfaces is an interesting alternative to isolate enantiopure antipodes. Herein, we take advantage of the outstanding enantiorecognition capabilities of inherently chiral oligomers to induce an enantioselective crystallization process. We exemplify this strategy with two amino acid model molecules, asparagine and glutamic acid, having a completely uncorrelated structure with respect to the template. This illustrates the versatility of the approach with potential applications in the resolution of pharmaceutical compounds.
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