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Updated: Jul 22, 2025

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Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
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A Sticky Situation: Glue Migration during Hepatic Vein Embolization.
Koustav Pal1, Joshua D Kuban1, Ravi Murthy1
1Department of Interventional Radiology, The University of Texas MD Anderson Cancer Center, Houston, Texas.
Seminars in Interventional Radiology
|July 24, 2023
Summary
Hepatic vein embolization, combined with portal vein embolization, can enhance future liver remnant hypertrophy before major liver surgery. A case report details managing an unintended glue cast migration during this procedure.
Area of Science:
- Interventional Radiology
- Hepatobiliary Surgery
- Vascular Embolization
Background:
- Major hepatectomy necessitates adequate future liver remnant (FLR) volume.
- Ipsilateral liver venous deprivation via hepatic vein embolization (HVE) alongside portal vein embolization (PVE) aims to maximize FLR hypertrophy.
- HVE is an emerging technique with potential complications.
Purpose of the Study:
- To present a case of HVE complicated by glue cast migration.
- To describe the endovascular management of glue cast embolization in the inferior vena cava (IVC).
- To discuss the role and risks of HVE in liver surgery preparation.
Main Methods:
- The study describes a case involving HVE combined with PVE prior to major hepatectomy.
- A glue cast used for hepatic venous occlusion migrated into the IVC.
- Endovascular retrieval of the misplaced glue cast was performed.
Main Results:
- The case highlights a rare complication of HVE: unintended migration of embolic material.
- Successful endovascular retrieval of the glue cast from the IVC was achieved.
- The management strategy for this specific complication is demonstrated.
Conclusions:
- HVE is a technique that can augment FLR hypertrophy but carries risks.
- Complications such as embolic material migration require prompt and effective endovascular management.
- Further understanding of HVE's role and safety profile is warranted in the context of major hepatectomy.
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