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Related Experiment Video

Updated: Jul 22, 2025

The In ovo CAM-assay as a Xenograft Model for Sarcoma

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Extraskeletal myxoid chondrosarcoma: a case report.

Anass Haloui¹, Nassira Karich¹, Asmae Aissaoui¹

¹Laboratory of Pathological Anatomy, Mohammed VI University Hospital, Faculty of Medicine and Pharmacy of Oujda, Mohammed First University, Oujda, Morocco.

The Pan African Medical Journal

|July 24, 2023

Summary

Extraskeletal myxoid chondrosarcoma is a rare soft tissue sarcoma. This case highlights its key features, aiding diagnosis of this challenging tumor.

Keywords:

Extraskeletal myxoid chondrosarcoma case report sarcoma soft tissue

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Area of Science:

Pathology
Oncology
Genetics

Background:

Extraskeletal myxoid chondrosarcoma (EMC) is a rare mesenchymal neoplasm.
It is characterized by abundant myxoid stroma and specific cellular arrangements.

Observation:

This report details a case in a 74-year-old woman with a thigh mass.
The tumor exhibited typical morphologic features of EMC.

Findings:

The molecular hallmark of EMC is the NR4A3 gene fusion with EWSR1 or TAF15.
Immunohistochemistry and molecular testing are crucial for diagnosis.
Differential diagnosis can be challenging due to similar-looking tumors.

Implications:

Accurate diagnosis of EMC is vital for appropriate patient management.
Understanding the key diagnostic features aids in distinguishing EMC from mimics.
This case underscores the importance of integrated diagnostic approaches.