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Related Concept Videos

Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

150
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
150
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

408
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
408
Chronic Pancreatitis I: Introduction01:24

Chronic Pancreatitis I: Introduction

116
The pancreas, an elongated and flat gland situated behind the stomach, serves a vital function in digesting food and managing blood sugar levels.
Pancreatitis is the inflammation of the pancreas, which occurs when the immune system becomes active and causes swelling, pain, and disruptions in organ function. Pancreatitis can manifest as either an acute or chronic condition.
Acute pancreatitis arises suddenly and lasts for a brief duration, while chronic pancreatitis is a long-term affliction...
116
Chronic Bowel Disorders: Introduction01:17

Chronic Bowel Disorders: Introduction

489
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
489
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

115
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
115
Appendicitis-I: Introduction01:22

Appendicitis-I: Introduction

254
The appendix, a small, narrow, blind tube extending from the inferior part of the cecum, is widely regarded as a vestigial organ, having lost much of its original function through evolution. Despite its diminished role, the appendix can become inflamed, a condition known as appendicitis.
Etiology: Appendicitis can arise from various causes, primarily rooted in the obstruction of the appendix lumen. Factors contributing to this obstruction include fecal accumulation, lymphoid hyperplasia and, in...
254

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Related Experiment Video

Updated: Jul 22, 2025

Sodium Taurocholate Induced Severe Acute Pancreatitis in C57BL/6 Mice
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Common Pathology With Atypical Presentation: Acute Cholangitis.

Aidan Farrell1, Harshavardhan Sanekommu2, Pranav N Shah3

  • 1Internal Medicine, Hackensack Meridian School of Medicine, Nutley, USA.

Cureus
|July 24, 2023
PubMed
Summary

Acute cholangitis, a serious biliary infection, can present atypically in elderly patients. Early diagnosis and treatment, even with non-specific symptoms, are vital for positive outcomes.

Keywords:
acute cholangitisbiliary diseasescholecystectomycholedocholithiasisendoscopy ercp

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Area of Science:

  • Gastroenterology and Hepatology
  • Internal Medicine
  • Biliary Tract Diseases

Background:

  • Acute cholangitis is a critical biliary tree infection, often linked to gallstones, with potentially fatal outcomes if untreated.
  • Prompt identification and management are essential to prevent severe complications.

Observation:

  • An 84-year-old female presented with acute cholangitis exhibiting atypical symptoms of chest pain and cough.
  • This case highlights the infrequent presentation of classic signs like Charcot's triad and Reynold's pentad in elderly individuals.

Findings:

  • The patient received successful treatment involving endoscopic retrograde cholangiopancreatography (ERCP), antibiotics, and ursodeoxycholic acid.
  • The case underscores the diagnostic challenge posed by non-specific symptoms in the elderly population.

Implications:

  • Emphasizes the need for a broad differential diagnosis in elderly patients presenting with vague symptoms suggestive of biliary pathology.
  • Highlights the importance of considering acute cholangitis even in the absence of typical clinical signs in the elderly.
  • Demonstrates successful management of acute cholangitis with ERCP and medical therapy in an elderly patient with an unusual presentation.