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Related Concept Videos

Glaucoma: Overview01:25

Glaucoma: Overview

623
Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
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Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

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In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
481
Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

572
Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
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Lymphocytic Panhypophysitis Mimicking Glaucoma: Case Report.

Phillip Howard Keys1, Patrick J Hunt2, Clement Anozie1

  • 1John Sealy School of Medicine, University of Texas Medical Branch, Galveston, TX, USA.

Case Reports in Ophthalmology
|July 24, 2023
PubMed
Summary
This summary is machine-generated.

Lymphocytic hypophysitis (LH) is a rare pituitary inflammation often linked to autoimmunity. This case highlights that lymphocytic panhypophysitis (LPH) can mimic other conditions like glaucoma, even without typical hormonal symptoms.

Keywords:
AutoimmuneCase reportGlaucomaLymphocytic hypophysitisLymphocytic panhypophysitis

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Area of Science:

  • Endocrinology
  • Neuroimmunology
  • Pathology

Background:

  • Lymphocytic hypophysitis (LH) is an inflammatory disorder of the pituitary gland, often autoimmune.
  • It typically presents with mass effect and hormonal dysfunction.

Observation:

  • A case of lymphocytic panhypophysitis (LPH) involving the entire pituitary was misdiagnosed as glaucoma for years.
  • The patient lacked typical endocrinopathy, and imaging was delayed.

Findings:

  • The patient's LPH mimicked glaucoma due to visual field defects without hormonal symptoms.
  • Biopsy confirmed LPH, and the patient improved with surgery and glucocorticoids.

Implications:

  • LPH can present without endocrinopathy, potentially mimicking other conditions.
  • Clinicians should consider LPH in patients with unexplained visual defects, especially with autoimmune history.
  • Early imaging is crucial for accurate diagnosis and timely treatment of LPH.