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Published on: September 8, 2013
Silylacylation of Alkenes through N-Heterocyclic Carbene Catalysis
Huiwei Xu1, Wanyao Zheng1, Wen-Deng Liu1
1School of Chemistry, Dalian University of Technology, Dalian 116024, China.
Abstract:
The construction of silicon-containing molecules has received increasing attention in recent years. Herein, we report the generation of silyl radicals through NHC catalysis under mild reaction conditions. This methodology offers a novel and convenient route to a diverse range of β-silyl ketones with a broad substrate scope and good functional group compatibility. Both the radical clock and electrochemical studies are consistent with the hypothesis of ground-state SET, and a plausible mechanism for the organocatalytic transformation is proposed.
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