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Related Experiment Video

Updated: Jul 22, 2025

Transplantation of a 3D Bioprinted Patch in a Murine Model of Myocardial Infarction
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Left ventricular assist device explantation using a new double-patch technique†.

Oliver Daniel Bhadra1, Jonas Pausch1, Hug Aubin2

  • 1University Heart & Vascular Center Hamburg, Department for Cardiovascular Surgery, Hamburg, Germany.

Interdisciplinary Cardiovascular and Thoracic Surgery
|July 24, 2023
PubMed
Summary
This summary is machine-generated.

Left ventricular assist device (LVAD) explantation is feasible and safe using a novel double-patch technique. This method ensures 100% survival and no complications, allowing anticoagulation discontinuation.

Keywords:
Heart failureLeft Ventricular Assist Device ExplantationLeft Ventricular Assist Device weaningMechanical Circulatory Support

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Area of Science:

  • Cardiology
  • Cardiovascular Surgery
  • Medical Devices

Background:

  • Surgical options for left ventricular assist device (LVAD) explantation after cardiac recovery vary.
  • Residual LVAD components pose risks of infection and thrombosis.
  • A new double-patch technique for LVAD explantation is presented.

Purpose of the Study:

  • To report a novel double-patch technique for LVAD explantation.
  • To evaluate the safety and feasibility of this technique in a two-center experience.
  • To assess outcomes including survival and complications.

Main Methods:

  • Five patients underwent LVAD explantation (HVAD: 2, HeartMate 3: 3) between March 2019 and April 2021.
  • The procedure involved median sternotomy, cardiopulmonary bypass, and a double-patch closure (pericardial and Gore-Tex) of the apex.
  • Mean patient age was 50.3 years; mean time on LVAD was 23.1 months.

Main Results:

  • All five LVAD explantations were technically uncomplicated.
  • 100% survival was observed during a mean follow-up of 16.4 months.
  • No bleeding complications or thromboembolic events occurred.

Conclusions:

  • LVAD explantation using the double-patch technique is feasible and safe.
  • This technique permits the discontinuation of anticoagulation.
  • 100% 30-day survival was achieved, warranting further long-term follow-up studies.