Biosensors based on core-shell nanoparticles for detecting mycotoxins in food: A review

Mycotoxins are toxic metabolites produced by fungi in the process of infecting agricultural products, posing serious threat to the health of human and animals. Thus, sensitive and reliable analytical techniques for mycotoxin detection are needed. Biosensors equipped with antibodies or aptamers as recognition elements and core-shell nanoparticles (NPs) for the pre-treatment and detection of mycotoxins have been extensively studied. By comparison with monocomponent NPs, core-shell nanostructures exhibit unique optical, electric, magnetic, plasmonic, and catalytic properties due to the combination of functionalities and synergistic effects, resulting in significant improvement of sensing capacities in various platforms, such as surface-enhanced Raman spectroscopy, fluorescence, lateral flow immunoassay and electrochemical sensors. This review focused on the development of core-shell NPs based biosensors for the sensitive and accurate detection of mycotoxins in food samples. Recent developments were categorised and summarised, along with detailed discussion of advantages and shortcomings. The future potential of utilising core-shell NPs in food safety testing was also highlighted.