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Published on: May 31, 2020
Association of ABO blood types and clinical variables with COVID-19 infection severity in Libya
Sara A Abdulla1, Hayam A Elawamy2, Negia Ae Mohamed1
1Department of Biochemistry, Faculty of Medicine, University of Benghazi, Benghazi, Libya.
Insights
This study identified key COVID-19 risk factors in Libya, finding males, adults over 31, and those with chronic conditions like diabetes and hypertension are more susceptible. Smoking also poses a risk for older adults.
Area of Science:
- Epidemiology
- Public Health
Background:
- The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), continues to pose a global health emergency.
- Addressing the COVID-19 situation in Libya requires enhanced understanding of disease trends and risk factors.
Purpose of the Study:
- To investigate the demographics and infection trends of COVID-19 in Libya.
- To identify potential risk factors associated with COVID-19 infection within the Libyan population.
Main Methods:
- A retrospective case-control study was conducted online.
- Data from 616 COVID-19 patients were analyzed using logistic regression.
- Statistical significance was determined using p-values, odds ratios, and 95% confidence intervals.
Main Results:
- Males exhibited a higher risk of COVID-19 infection (OR=1.3, p=0.02).
- Anosmia and ageusia were more prevalent in females.
- Individuals with blood group AB, adults aged 31 and above, smokers over 60, and those with diabetes or hypertension showed increased susceptibility.
- Chronic conditions like diabetes (OR=10.045, p=0.000) and hypertension (OR=11.508, p=0.000) were significant risk factors.
Conclusions:
- This study provides the first demographic data and infection trends for COVID-19 in Libya.
- Findings will aid stakeholders and government bodies in developing effective pandemic protection strategies.
Objective:
The continuing COVID-19 pandemic is a coronavirus-related health emergency (severe acute respiratory syndrome coronavirus 2). Inadequate efforts are still being made to address the illness situation in Libya, and this must change. To address these issues, we looked into the demography and trend of the disease as well as the potential risk factors for infection.
Methods:
This study is a retrospective case-control study conducted online among 616 COVID-19 patients. The p0.05 value, odds ratios, and 95% confidence intervals were calculated and analyzed from the drawn data.
Results:
Males were at high risk of COVID-19 than females (odds ratio = 1.3, 95% confidence interval: 1.042-1.622; p = 0.02). Anosmia and ageusia were more prominent in females. Patients with an "AB" blood group are significantly susceptible to infection. Adults (31 and above) are highly liable to infection. The univariate logistic regression analysis revealed that smoking is a risk factor for those above 60 years (odds ratio = 2.228, 95% confidence interval: 1.145-4.336; p = 0.018). Individuals with chronic diseases such as diabetes and/or hypertension are more prone to COVID-19 (odds ratio = 10.045, 95% confidence interval: 3.078-32.794; p = 0.000 and odds ratio = 11.508, 95% confidence interval: 3.930-33.695; p = 0.000, respectively).
Conclusion:
This study provided for the first time the demographic data and the trend of COVID-19 infection in Libya, which will assist the stakeholders and governmental bodies in planning protection strategies against the pandemic.
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