Variations in Microcirculatory and Hemodynamic Parameters during Oncological Demolitive-Reconstructive Head and Neck...

Area of Science:

• Oncology
• Vascular Surgery
• Anesthesiology

Background:

• Head and neck oncological surgeries induce significant physiological stress, impacting macrocirculatory and microcirculatory parameters.
• Current monitoring often misses underlying causes, highlighting the need for advanced microcirculation assessment.
• Optimal tissue perfusion is critical during flap reconstruction, yet consensus on macro-microcirculation coupling and vasopressor use is lacking.

Purpose of the Study:

• To investigate the relationship between macro- and microcirculation coupling in head and neck cancer surgery.
• To assess hemodynamic parameters and microcirculatory alterations during these complex procedures.
• To determine the association between circulatory coupling and postoperative complications.

Main Methods:

• A 12-month prospective, observational study at a single center.
• Inclusion of consecutive patients undergoing oncologic head and neck surgery with flap reconstruction.
• Utilizing standard hemodynamic monitoring alongside bladder catheterization for urine output and temperature monitoring.

Main Results:

• Data collection ongoing; results pending.
• Analysis will focus on correlating hemodynamic and microcirculatory data with clinical outcomes.
• Expected to provide insights into circulatory dynamics during oncologic head and neck reconstruction.

Conclusions:

• The study aims to elucidate the interplay between macro- and microcirculation in high-risk surgical patients.
• Findings are expected to inform evidence-based guidelines for perioperative management.
• Potential to improve patient care and surgical outcomes in head and neck oncology.