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Ocular involvement in allergic drug reactions
Edward Fernandez1, Elizabeth Phillips1,2, Hajirah N Saeed3,4
1Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University School of Medicine.
Current Opinion in Allergy and Clinical Immunology
|July 26, 2023
Summary
Systemic medications can cause ocular toxicity through immune responses. Early recognition and ophthalmologist involvement are crucial for managing these drug reactions and preserving vision.
Area of Science:
- Ophthalmology
- Immunology
- Pharmacology
Background:
- Systemic medications are increasingly associated with ocular toxicity.
- A subset of these ocular adverse drug reactions involves immunomodulation or hypersensitivity.
- The prevalence of ocular adverse effects from new medications is rising.
Conclusions:
- Clinicians must be aware of immune-mediated ocular adverse drug reactions for early detection.
- Prompt ophthalmologist consultation is essential for diagnosis and management.
- Timely intervention can preserve vision and prevent long-term morbidity.
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