Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

EVERolimus effectiveness after proGREssion on ENdocrine therapy plus CDK4/6 inhibitor for ER-positive/HER2-negative advanced breast cancer: EVERGREEN study.

Breast cancer research and treatment·2026
Same author

ASO Visual Abstract: Correlations between the Histological Growth Patterns of Peritoneal and Liver Metastases from Colorectal Cancer.

Annals of surgical oncology·2026
Same author

Correlations Between the Histologic Growth Patterns of Peritoneal and Liver Metastases From Colorectal Cancer.

Annals of surgical oncology·2026
Same author

Neoadjuvant stereotactic body radiation therapy with durvalumab and oleclumab in ER<sup>+</sup>HER2<sup>-</sup> breast cancer: a randomized phase 2 trial.

Nature medicine·2026
Same author

Intraoperative breast cancer margin evaluation using fluorescence imaging with intravenous injection of indocyanine green (BREASTIFLU-1): study protocol for a randomized diagnostic accuracy trial of quantitative dose-timing assessment.

Trials·2026
Same author

Spatial transcriptomics reveals tumor microenvironment-driven subtypes of invasive lobular carcinoma.

Proceedings of the National Academy of Sciences of the United States of America·2026

Related Experiment Video

Updated: Jul 21, 2025

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models
13:43

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models

Published on: April 1, 2022

4.6K

Effectiveness of Carbon Localization for Invasive Breast Cancer: An Institutional Experience.

Etienne El-Helou1, Christine Eddy1, Simona Picchia2

  • 1Department of Surgery, Institut Jules Bordet, Université Libre de Bruxelles, Brussels, Belgium.

The Breast Journal
|July 27, 2023
PubMed
Summary

Carbon localization (CL) effectively identifies breast cancer (BC) tumors for breast-conserving surgery (BCS). This technique achieved a 99% identification rate and 93.4% complete resection, ensuring successful BC lesion excision.

More Related Videos

X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models
12:57

X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models

Published on: December 9, 2022

2.4K
Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad
07:05

Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad

Published on: January 20, 2019

51.6K

Related Experiment Videos

Last Updated: Jul 21, 2025

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models
13:43

Intraductal Delivery and X-ray Visualization of Ethanol-Based Ablative Solution for Prevention and Local Treatment of Breast Cancer in Mouse Models

Published on: April 1, 2022

4.6K
X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models
12:57

X-Ray Visualization of Intraductal Ethanol-Based Ablative Treatment for Prevention of Breast Cancer in Rat Models

Published on: December 9, 2022

2.4K
Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad
07:05

Orthotopic Injection of Breast Cancer Cells into the Mice Mammary Fat Pad

Published on: January 20, 2019

51.6K

Area of Science:

  • Oncology
  • Surgical Oncology
  • Radiology

Background:

  • Breast-conserving surgery (BCS) outcomes depend on precise tumor localization and margin assessment.
  • Effective localization techniques are crucial for successful breast cancer (BC) excision during BCS.

Purpose of the Study:

  • To evaluate the effectiveness of the carbon localization (CL) technique for BC.
  • To determine the success rate of BC identification and complete resection using CL.

Main Methods:

  • Retrospective cross-sectional study of 542 patients undergoing primary BCS with CL.
  • Analysis of tumor identification and adequate excision rates using descriptive statistics.
  • CL performed under ultrasound guidance in 98.5% of cases.

Main Results:

  • Successful one-stage complete resection in 93.4% of cases.
  • Tumor identification in the surgical specimen achieved 98.9%.
  • Median pathological tumor size was 12 mm; 460 cases were invasive ductal carcinomas.

Conclusions:

  • CL demonstrates high success rates for BC tumor identification (99%) and complete resection (93.4%) in BCS.
  • CL is an effective, simple, and inexpensive method for BC lesion excision during BCS.