[Pleural mesothelioma. Developmental and therapeutic aspects apropos of 37 cases]

Thirty-seven cases of pleural mesothelioma seen in our unit between 1974 and 1984 have been reviewed. In cases with limited lesions early thoracotomy with an attempt at pleurectomy/lung decortication seemed to be justified. Thereafter - or initially in patients with extensive lesions - we resort to radiotherapy and/or chemotherapy. Although the final result was mediocre, we found it difficult to abstain from any treatment. Owing to the lack of large series and to the heterogeneity of those that have been published, no fixed rule can be laid down for the treatment of mesothelioma. Nevertheless, it would appear that using multiple therapeutic methods results in a somewhat longer survival.