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ABR in multiple sclerosis. Ipsi- versus contralateral derivation.

A Quaranta, F Mininni, G Longo

    Scandinavian Audiology
    |January 1, 1986
    PubMed
    Summary
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    Contralateral ear lobe recordings significantly improve the detection of multiple sclerosis (MS) using brainstem auditory evoked potentials (ABR). This method enhances diagnostic accuracy in both confirmed and undefined MS cases.

    Area of Science:

    • Neuroscience
    • Audiology
    • Neurology

    Background:

    • Multiple Sclerosis (MS) can affect auditory pathways, necessitating reliable diagnostic tools.
    • Brainstem Auditory Evoked Potentials (BAEPs) are used to assess auditory pathway integrity.
    • Standard BAEPs may not always detect subtle neurological changes.

    Purpose of the Study:

    • To evaluate the efficacy of contralateral ear lobe derivations in BAEP recordings for diagnosing MS.
    • To compare the diagnostic yield of ipsilateral versus contralateral BAEPs in MS patients.

    Main Methods:

    • Brainstem Auditory Evoked Potentials (BAEPs) were recorded in 53 MS patients (19 confirmed, 34 undefined) and 20 controls.
    • Simultaneous recordings were made between vertex and ear lobe, ipsilateral and contralateral to the stimulated ear.

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  • Abnormality was defined by wave absence or significant latency differences.

    • Main Results:

    • Contralateral derivations increased BAEP abnormality detection rates in confirmed MS from 74% to 89%.
    • Detection rates for undefined MS improved from 9% to 21% using contralateral recordings.
    • Significant latency differences were observed between ipsilateral and contralateral recordings in controls.

    Conclusions:

    • Contralateral ear lobe derivations enhance the sensitivity of BAEPs for MS detection.
    • Incorporating contralateral BAEP parameters can improve otoneurological diagnostic criteria for central nervous system lesions.
    • This technique offers a valuable adjunct for diagnosing MS, especially in early or less defined cases.