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Probable West Nile Virus hepatitis: Case report.

Giovanni Mori1, Martina Strano1, Matteo Chiurlo1

  • 1Vita-Salute San Raffaele University, 20132 Milan, Italy.

Idcases
|July 28, 2023
PubMed
Summary

West Nile Virus (WNV) infections are common, usually causing fever. This case highlights WNV-mediated hepatitis, a rare but possibly overlooked manifestation of the virus.

Keywords:
ArbovirusEmerging diseasesHepatitisVisceral diseaseWest Nile Virus

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Area of Science:

  • Medicine
  • Virology
  • Hepatology

Background:

  • West Nile Virus (WNV) is a globally endemic flavivirus.
  • WNV infections typically present as acute febrile illness.
  • Neuroinvasive disease occurs in less than 1% of symptomatic cases.

Observation:

  • This report details a rare case of probable WNV-mediated isolated hepatitis.
  • The patient presented with liver inflammation without typical neurological symptoms.

Findings:

  • The findings suggest WNV can cause isolated hepatitis.
  • This presentation is infrequently recognized in clinical practice.

Implications:

  • WNV-mediated hepatitis may be an underestimated clinical manifestation.
  • Clinicians should consider WNV in the differential diagnosis of hepatitis, especially in endemic areas.
  • Further research is needed to understand the prevalence and mechanisms of WNV-induced liver injury.