[Differential diagnosis of jaundice based on antipyrine metabolism]

The investigation of detoxicating function of the liver in 85 patients has shown that the indices of antipyrine clearance in patients with one-month-long parenchymatous jaundice and obstructive cholestasis were reliably different. However, longer terms of mechanical jaundice with concomitant pronounced cholangiohepatitis made the liver metabolism progressively worse. The authors recommend using antipyrine tests in differential diagnostics of parenchymatous and mechanical jaundice.