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Pulsed Electromagnetic Fields (PEMF)-Physiological Response and Its Potential in Trauma Treatment
Jonas Flatscher1, Elizabeth Pavez Loriè1, Rainer Mittermayr2
1Ludwig Boltzmann Institute for Traumatology, The Research Center in Cooperation with AUVA, 1200 Vienna, Austria.
International Journal of Molecular Sciences
|July 29, 2023
Summary
Pulsed Electromagnetic Fields (PEMF) show promise for trauma recovery, but varied study methods hinder understanding. This review synthesizes research to identify common parameters for better mechanistic insights into PEMF therapy.
Area of Science:
- Biophysics
- Cellular Biology
- Orthopedics
Background:
- Environmental biophysical interactions are crucial for human trauma recovery.
- Pulsed Electromagnetic Fields (PEMF) have demonstrated positive clinical effects, particularly in orthopedics.
- Decades of research exist on PEMF's impact on human biological and cellular systems.
Purpose of the Study:
- To provide a comprehensive overview of existing Pulsed Electromagnetic Fields (PEMF) literature.
- To identify commonalities and discrepancies in study setups, parameters, and outcomes.
- To facilitate a deeper mechanistic understanding of PEMF therapy for trauma recovery.
Main Methods:
- Systematic review of published studies on PEMF.
- Categorization of literature from broad reviews to individual studies.
- Analysis of physical parameters, molecular/cellular responses, and clinical outcomes.
Main Results:
- Significant diversity exists in PEMF study methodologies and reporting.
- Identifying common reporting parameters is challenging but essential.
- Observed positive clinical effects in orthopedics drive research interest.
Conclusions:
- A unified understanding of PEMF mechanisms is hindered by study variability.
- Standardizing reporting parameters is crucial for advancing PEMF research.
- This review serves as a scaffold for future research and clinical application of PEMF.

