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Effect of Flow Velocity on Laminar Flow in Microfluidic Chips
Chuang Wu1,2,3, Haithm Yahya Mohammed Almuaalemi1, A S M Muhtasim Fuad Sohan4
1School of Mechanical Engineering, Yangzhou University, Yangzhou 225127, China.
Micromachines
|July 29, 2023
Summary
Researchers optimized microfluidic laminar flow for fabricating gel fibers. Stable laminar flow and well-shaped fibers were achieved at a flow rate of 1 mL/h with specific sodium alginate and CaCl2 concentrations.
Area of Science:
- Biomaterials Engineering
- Fluid Dynamics
- Tissue Engineering
Background:
- Microfluidic laminar flow technology is crucial for creating biomimetic scaffolds.
- Controlling fluid flow rate is key to successful microfluidic applications.
Purpose of the Study:
- To investigate the influence of fluid flow rate on laminar flow in microfluidic chips.
- To optimize conditions for stable laminar flow and gel fiber fabrication.
Main Methods:
- Designed a microfluidic chip with a main pipe and surrounding outer pipes.
- Fabricated the chip using photolithography and composite molding.
- Utilized syringe pumps and fluid dynamics simulation for analysis.
Main Results:
- Identified optimal concentrations: 1 wt% sodium alginate (outer phase) and 0.1 wt% CaCl2 (inner phase).
- Achieved stable laminar flow and well-formed gel fibers at a flow rate of 1 mL/h for both fluids.
- Demonstrated the most obvious laminar flow phenomenon under these conditions.
Conclusions:
- The study provides a preliminary achievement in exploring microfluidic laminar flow rates for gel fiber fabrication.
- Findings offer significant reference value for advancing microfluidic laminar flow technology.
- Optimized parameters enable the production of high-quality biomimetic scaffolds.
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