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Nanozyme-Powered Multimodal Sensing for Pesticide Detection
Binfeng Yin1, Zhuoao Jiang1, Rashid Muhammad1
1School of Mechanical Engineering, Yangzhou University, Yangzhou 225127, China.
Foods (Basel, Switzerland)
|June 13, 2025
Summary
Nanozymes offer a cost-effective and sensitive solution for detecting harmful pesticide residues in food, overcoming limitations of traditional methods. This review explores their diverse applications and future potential, including integration with artificial intelligence (AI).
Area of Science:
- Analytical Chemistry
- Materials Science
- Food Science
Background:
- Pesticide residue detection is vital for food safety and public health.
- Traditional detection methods are precise but costly and labor-intensive.
- Nanozymes present a promising alternative due to their low cost, high stability, and sensitivity.
Purpose of the Study:
- To review the advancements in nanozyme-based pesticide residue detection over the past decade.
- To explore various nanozyme types, their synthesis, and catalytic mechanisms.
- To discuss multimodal sensing strategies and the role of AI in this field.
Main Methods:
- Review of research on carbon-based, metal-based, metal-oxide-based, MOF-based, and fluorescence-based nanozymes.
- Analysis of multimodal sensing techniques (e.g., colorimetric/fluorescence, fluorescence/photothermal).
- Examination of nanozyme applications in conjunction with artificial intelligence (AI).
Main Results:
- Nanozymes demonstrate significant potential for sensitive and cost-effective pesticide detection.
- Various nanozyme platforms (carbon, metal, MOF, etc.) show diverse catalytic mechanisms.
- Multimodal sensing and AI integration enhance detection capabilities and address challenges.
Conclusions:
- Nanozymes are a viable and advancing technology for detecting pesticide residues in food.
- Further research is needed to overcome current challenges and optimize AI integration.
- This review provides guidance for selecting nanozymes and detection methods for pesticide analysis.

