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Polypropylene-Based Polymer Locking Ligation System Manufacturing by the Ultrasonic Micromolding Process
Alex Elías-Grajeda1, Elisa Vázquez-Lepe1, Héctor R Siller2
1Tecnologico de Monterrey, Institute of Advanced Materials for Sustainable Manufacturing, Av. Eugenio Garza Sada Sur 2501, Monterrey 64849, N.L., Mexico.
Polymers
|July 29, 2023
Summary
Ultrasonic molding (USM) successfully produced biocompatible microdevices for surgery. Optimal quality was achieved with specific processing parameters, enhancing thermal stability.
Area of Science:
- Biomaterials Science
- Medical Device Manufacturing
- Polymer Engineering
Background:
- Growing demand for microscale biocompatible medical devices.
- Challenges in manufacturing intricate microfeatures for medical applications.
- Need for advanced manufacturing techniques to meet these demands.
Purpose of the Study:
- To investigate ultrasonic molding (USM) for producing microdevices.
- To manufacture the Hem-O-Lok surgical ligation device using USM.
- To optimize USM processing parameters for high-quality microdevice production.
Main Methods:
- Utilized ultrasonic molding (USM) technology.
- Employed a nonabsorbable biopolymer for microdevice fabrication.
- Investigated processing parameters: vibration amplitude, temperature, and injection velocity.
- Conducted materials characterization to assess microfeature quality and thermal stability.
Main Results:
- Successfully manufactured the Hem-O-Lok microdevice with USM.
- Identified optimal USM conditions: maximum vibrational amplitude and temperatures of 50-60 °C.
- Confirmed high quality of critical microfeatures.
- Detected a carbonyl (C=O) group from thermo-oxidation, enhancing thermal stability up to 437 °C.
Conclusions:
- Ultrasonic molding is a viable technique for producing complex biocompatible microdevices.
- Optimized processing parameters are crucial for achieving high-quality microdevices.
- The biopolymer exhibits enhanced thermal stability suitable for medical applications.
