Practical Application of Culture-Directed Treatment for Chronic Bacterial Laryngitis
Keith R Conti1, Adelaide Zhao2, Erin Hunt1
1Division of Otolaryngology, Department of Surgery, St. Luke's University Health Network, Bethlehem, Pennsylvania, U.S.A.
The Laryngoscope
|July 29, 2023
Summary
Culture-directed therapy for chronic infectious laryngitis aided treatment decisions. This study highlights the effectiveness of targeted treatments for bacterial and fungal infections of the larynx.
Area of Science:
- Otolaryngology
- Infectious Diseases
- Microbiology
Background:
- The larynx is susceptible to infections, causing symptoms like hoarseness and sore throat.
- Chronic infectious laryngitis requires a better understanding of patient characteristics and clinical presentation.
Purpose of the Study:
- To investigate the clinical presentation and patient characteristics of chronic infectious laryngitis.
- To determine the utility of culture-directed therapy for chronic infectious laryngitis.
Main Methods:
- Retrospective chart review of patients with laryngitis (>3 weeks) and positive laryngeal cultures.
- Data collected from a single tertiary referral laryngology office (January 2016 - January 2023).
Main Results:
- Twenty-four patients (36-84 years) with 29 positive laryngeal cultures were analyzed.
- Common bacteria included Klebsiella sp. and Staphylococcus sp.; 41.4% had multiple species, 34.5% had fungal isolates.
- 72% of patients improved with culture-directed therapy (average 10-day treatment).
Conclusions:
- Culture-directed therapy is valuable for treating chronic bacterial laryngitis.
- Further research is needed on optimal timing for cultures, treatment duration, and fungal laryngitis.
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