Risk factors for hypothyroidism following hemithyroidectomy

Area of Science:

• Endocrinology
• Surgical Oncology

Background:

• Hypothyroidism is a frequent complication after hemithyroidectomy for thyroid nodules.
• Identifying predictive factors is crucial for patient management.

Purpose of the Study:

• To investigate prognostic factors for hypothyroidism following hemithyroidectomy.
• To identify patients at higher risk for postoperative hypothyroidism.

Main Methods:

• Retrospective cohort study of 128 patients undergoing hemithyroidectomy (2016-2017).
• Exclusion of patients with preoperative hypothyroidism or malignancy.
• Primary endpoint: development of hypothyroidism (TSH ≥ 2 above normal).

Main Results:

• 20% of patients developed hypothyroidism post-surgery.
• Independent predictors identified: preoperative TSH > 1.5 mIU/L and remaining thyroid volume < 4.0 mL/m².
• Postoperative TSH levels correlated significantly with preoperative values.

Conclusions:

• Patients with preoperative TSH > 1.5 mIU/L or small remaining thyroid volume require intensified clinical and biological follow-up.
• Early detection and management of hypothyroidism post-hemithyroidectomy are essential.