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Prolonged Corticosteroid Use Leading to Cerebral Venous Sinus Thrombosis: A Rare Association

Vikram Jain1, Jaideep Pilania1, Mayank Agarwal1

  • 1Internal Medicine, All India Institute of Medical Sciences, Rishikesh, IND.

Cureus
|July 31, 2023
PubMed

Insights

Cerebral venous sinus thrombosis (CVST) can result from blocked brain blood flow. Chronic steroid use, common in athletes for weight gain, may increase CVST risk, as seen in a young male bodybuilder case.

Area of Science:

  • Neurology
  • Vascular Medicine
  • Endocrinology

Background:

  • Cerebral venous sinus thrombosis (CVST) is a condition involving obstruction of venous blood flow in the brain.
  • Prothrombotic conditions, both acquired and inherited, are common risk factors for CVST.
  • Exogenous steroid use for weight gain is prevalent among athletes and bodybuilders.

Observation:

  • Excessive exogenous steroid intake is associated with increased risk of venous thromboembolism.
  • The specific link between steroid use and CVST in athletes has been infrequently reported.
  • A case study involved a young male bodybuilder with a history of chronic steroid use presenting with CVST symptoms.

Findings:

  • The patient exhibited clinical signs consistent with cerebral venous sinus thrombosis.
  • Chronic exogenous steroid intake was identified as a significant factor in this patient's presentation.
  • This case highlights a potential, underreported risk factor for CVST in specific populations.

Implications:

  • Increased awareness of CVST risk associated with anabolic steroid use in athletes is warranted.
  • Further research is needed to elucidate the mechanisms linking steroid use to cerebral venous thrombosis.
  • Clinical vigilance for CVST should be considered in athletes presenting with relevant symptoms and a history of steroid use.

Keywords:
cerebral sinuscerebral venous sinus thrombosiscorticosteroidsthrombosisvenousyoung male

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