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Updated: Jul 20, 2025

Full-Field Optical Coherence Microscopy for Histology-Like Analysis of Stromal Features in Corneal Grafts
Published on: October 21, 2022
The measurement of Central Corneal Thickness
Georgiana Camburu1, Mihail Zemba1, Călin Petru Tătaru1
1"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.
Abstract:
We aimed to compare five different devices that measure Central Corneal Thickness. The Central Corneal Thickness (CCT) is an important parameter in ophthalmology. It is involved in the management of various eye conditions such as: glaucoma, keratoconus, contact lens wearing, corneal dystrophies, refractive surgery and keratoplasty. We measured the CCT using OCT, Topographer (TOPO), Ultrasonography Pachymeter (US), Specular Microscope (MS), and Non-contact Tonometer (TONO). In the analysis of the data collected from 59 patients we found the following mean values: US - 554.51 ± 29.849 μm, OCT - 548.73 ± 31.080 μm, TOPO - 553.76 ± 29.845 μm, MS - 564 ± 32.637 μm, and TONO - 538.9 ± 35.657 μm. Our results confirmed the strong correlation between techniques. Abbreviations: OCT = Optical Coherence Tomography, CCT = Central Corneal Thickness, TOPO = Topographer, US = Ultrasonography Pachymeter, MS = Specular Microscope, TONO = Non-contact Tonometer.
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