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Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
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Microbiota associated with peri-implantitis-A systematic review with meta-analyses
Érika B S Carvalho1, Mario Romandini2, Sofya Sadilina3
1Department of Prosthodontics and Periodontics, Bauru School of Dentistry, University of Sao Paulo, Bauru, Sao Paulo, Brazil.
Clinical Oral Implants Research
|July 31, 2023
Summary
Peri-implantitis is linked to specific bacteria like Staphylococcus epidermidis and periodontal pathogens such as Porphyromonas gingivalis. These bacterial differences help distinguish peri-implantitis from healthy peri-implant sites.
Area of Science:
- Microbiology
- Periodontology
- Biomaterials
Background:
- Peri-implantitis is a prevalent complication following dental implant placement.
- Understanding the microbial differences between peri-implantitis and peri-implant health is crucial for diagnosis and treatment.
Approach:
- A systematic review and meta-analysis was conducted to compare bacterial presence in peri-implantitis versus peri-implant health/mucositis.
- Twelve cross-sectional studies involving 1233 participants and 1513 implants were included.
- Risk of bias was assessed, and results were synthesized using random-effects meta-analyses.
Key Points:
- Peri-implantitis showed a significant association with Staphylococcus epidermidis (OR=10.28).
- Specific periodontopathogens like *F. nucleatum* (OR=7.83), *T. denticola* (OR=6.11), *T. forsythia* (OR=4.25), *P. intermedia* (OR=3.79), and *P. gingivalis* (OR=2.46) were also linked to peri-implantitis.
- No significant association was found between peri-implantitis and *A. actinomycetemcomitans*, *S. aureus*, or *C. rectus*.
Conclusions:
- Peri-implantitis is characterized by the presence of *S. epidermidis* and key periodontopathogens.
- These findings highlight specific bacterial markers for differentiating peri-implantitis from healthy conditions.
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