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Overt Hypothyroidism Status Post Pfizer-BioNTech Vaccination: A Case Study.

Sailaja Nandennagari¹, Preethi Annam², Nithish Naidu³

¹Medicine, Avalon University School of Medicine, Willemstad, CUW.

|August 1, 2023

Summary

COVID-19 vaccination with Pfizer-BioNTech is linked to rare thyroid dysfunction. A case report details hypothyroidism developing weeks after receiving the vaccine.

Keywords:

covid 19 vaccination covid-19 covid-19 vaccine adverse effects covid-19 vaccine side effects hypothyroidism pandemic pfizer vaccination

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Area of Science:

Endocrinology
Immunology
Public Health

Background:

COVID-19 vaccination is crucial for controlling the pandemic.
Several vaccine types, including Pfizer-BioNTech, have been approved.
While common side effects are known, rare adverse events like thyroid dysfunction are still being investigated.

Observation:

Thyroid dysfunction is an uncommon side effect reported post-COVID-19 vaccination.
Existing literature includes case reports and series on vaccination-associated thyroid dysfunction.
The precise mechanisms linking vaccines to thyroid issues remain unclear.

Findings:

This report details a case of overt hypothyroidism in a 50-year-old woman.
Hypothyroidism was diagnosed three weeks after Pfizer-BioNTech vaccination.
The patient was previously healthy, with no prior thyroid history.

Implications:

This case highlights a potential rare adverse effect of COVID-19 vaccines.
Further research is needed to understand the pathophysiology of vaccine-induced thyroid dysfunction.
Clinicians should remain vigilant for atypical side effects following vaccination.