Related Experiment Video
Updated: Jul 20, 2025

Establishment of Rat Models Mimicking Gender-affirming Hormone Therapies
Published on: January 10, 2025
Prevalence of Psoriasis and Perceived Association with Hormone Therapy in Transgender Adults
Hayley Braun1, Elaine C Thompson1, Qi Zhang2
1Department of Dermatology, Emory University School of Medicine, Atlanta, Georgia, USA.
Purpose:
The role of hormone therapy (HT) in the etiology and progression of psoriasis in the transgender population is unclear.
Methods:
The prevalence of psoriasis in transmasculine (TM) and transfeminine (TF) adults and perceived links between psoriasis and gender-affirming HT is examined using a cross-sectional survey of 696 transgender individuals.
Results:
Ever diagnosis of psoriasis was reported by 17 TM persons (4.9%; 95% confidence interval [CI]: 2.6-7.2) and 13 TF persons (3.7%; 95% CI: 1.7-5.7). Prevalence of current psoriasis in TM persons was 2.6% (95% CI: 0.9-4.3) and 1.1% (95% CI: 0.03-2.3) among TF persons. Notably, among participants who had ever had psoriasis, 17% perceived a link between their psoriasis and gender-affirming HT.
Conclusions:
Prevalence of psoriasis among transgender persons resembled estimates in the general population. Potential associations between psoriasis and its severity with gender-affirming HT warrant further longitudinal research.
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