Related Experiment Video
Updated: Jul 20, 2025

Improved Renal Denervation Mitigated Hypertension Induced by Angiotensin II Infusion
Published on: May 26, 2022
Controlling Hypertension through Education and Coaching in Kidney Disease (CHECK-D): protocol of a cluster randomised
Julie A Wright Nunes1,2, Ken Resnicow3,4, Caroline Richardson5
1Department of Internal Medicine, Division of Nephrology, University of Michigan, Ann Arbor, Michigan, USA juwright@med.umich.edu.
Insights
This study tests if early education and motivational interviewing health coaching improve blood pressure control in chronic kidney disease (CKD) patients. The goal is to enhance patient knowledge and self-efficacy for better health outcomes.
Area of Science:
- Nephrology
- Public Health
- Health Education
Background:
- Chronic kidney disease (CKD) affects millions, with suboptimal blood pressure (BP) control being a major contributor to cardiovascular morbidity and mortality.
- Less than 40% of CKD patients achieve recommended BP targets due to barriers like poor understanding of their condition and self-management.
- Effective interventions are needed to improve patient engagement and adherence to BP management strategies in CKD.
Purpose of the Study:
- To evaluate the impact of early primary care-based CKD education combined with motivational interviewing (MI)-based health coaching on patient behaviors related to BP control.
- To assess the intervention's effect on increasing patient knowledge, self-efficacy, and motivation for managing CKD and BP.
- To provide data for developing sustainable, patient-centric interventions to improve quality of life and outcomes for CKD stages 3-5 patients.
Main Methods:
- A cluster randomized controlled trial involving 350 patients with CKD stages 3-5 in a primary care setting.
- The intervention group receives clinician-delivered education followed by 12 months of MI-based health coaching.
- Outcomes will be compared between the intervention and control groups, utilizing continuous quality improvement (CQI) and systems methodologies.
Main Results:
- This section is to be filled after the study's completion and data analysis.
- The study aims to demonstrate significant improvements in BP control metrics within the intervention group.
- Anticipated results include enhanced patient knowledge, increased self-efficacy, and higher motivation levels impacting health behaviors.
Conclusions:
- Early CKD education coupled with MI-based health coaching holds promise for improving BP control and patient outcomes.
- This multidisciplinary, patient-coaching approach can be integrated early in the CKD care continuum.
- Findings will inform future dissemination of effective, technology-supported interventions for CKD management.
Introduction:
Chronic kidney disease (CKD) affects 30 million Americans. Early management focused on blood pressure (BP) control decreases cardiovascular morbidity and mortality. Less than 40% of patients with CKD achieve recommended BP targets due to many barriers. These barriers include a lack of understanding of the implications of their diagnosis and how to optimise their health.This cluster randomised control trial hypothesises that the combination of early primary care CKD education, and motivational interviewing (MI)-based health coach support, will improve patient behaviours aligned with BP control by increasing patient knowledge, self-efficacy and motivation. The results will aid in sustainable interventions for future patient-centric education and coaching support to improve quality and outcomes in patients with CKD stages 3-5. Outcomes in patients with CKD stages 3-5 receiving the intervention will be compared with similar patients within a control group. Continuous quality improvement (CQI) and systems methodologies will be used to optimise resource neutrality and leverage existing technology to support implementation and future dissemination. The innovative approach of this research focuses on the importance of a multidisciplinary team, including off-site patient coaching, that can intervene early in the CKD care continuum by supporting patients with education and coaching.
Methods And Analysis:
We will test impact of BP control when clinician-delivered education is followed by 12 months of MI-based health coaching. We will compare outcomes in 350 patients with CKD stages 3-5 between intervention and control groups in primary care. CQI and systems methodologies will optimise education and coaching for future implementation and dissemination.
Ethics And Dissemination:
This study was approved by the University of Michigan Institutional Review Boards (IRBMED) HUM00136011, HUM00150672 and SITE00000092 and the results of the study will be published on ClinicalTrials.gov, in peer-reviewed journals, as well as conference abstracts, posters and presentations.
Trial Registration Number:
NCT04087798.
Related Concept Videos
Chronic Kidney Disease III: Interprofessional Care
Hypertension V: Nursing Management
Hypertension IV: Drug Therapy and Lifestyle Modifications
Chronic Kidney Disease IV: Nursing Management
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension and Regulation of Blood Pressure

