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Gold nanoparticles combat enveloped RNA virus by affecting organelle dynamics

Fangzhou Li1, Qianqian Huang1,2, Ziran Zhou1,2

  • 1CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety, CAS Center for Excellence in Nanoscience, National Center for Nanoscience and Technology of China, No. 11, First North Road, Zhongguancun, 100190, Beijing, P. R. China.

Signal Transduction and Targeted Therapy
|August 1, 2023
PubMed
Summary

Positively charged gold nanoparticles (AuNPs) disrupt cell organelles and exhibit antiviral effects against enveloped RNA viruses like lentivirus and human coronavirus OC43 (HCoV-OC43). These AuNPs show potential for targeting organelle dynamics for antiviral therapies.

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