Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Schottky Barrier Diode

Schottky Barrier Diode

Schottky barrier diodes are specialized semiconductor devices characterized by their unique construction. This construction involves combining a metal layer with a moderately doped n-type semiconductor material. This combination leads to the formation of a Schottky barrier, a pivotal element that defines the diode's operational characteristics. The core functionality of Schottky barrier diodes is their capacity to allow current to flow in only one direction due to their distinctive...

MOSFET: Depletion Mode

MOSFET: Depletion Mode

Depletion-mode MOSFETs represent a unique subset of MOSFET technology, functioning fundamentally differently from their enhancement-mode counterparts. Unlike enhancement MOSFETs, which require a positive gate-source voltage (Vgs) to turn on, depletion-mode MOSFETs are inherently conductive and "normally on" devices.
The primary characteristic of depletion-mode MOSFETs is their ability to conduct current between the drain and source terminals without gate bias. This inherent conductivity...

Non-gated Ion Channels

Non-gated Ion Channels

Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism....

Ligand-Gated Ion Channel Receptor: Gating Mechanism

Ligand-Gated Ion Channel Receptor: Gating Mechanism

Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...

Potentiometry: Membrane Electrodes

Potentiometry: Membrane Electrodes

Membrane electrodes, also known as p-ion electrodes, use membranes that selectively interact with free analyte ions, generating a potential difference across the membrane. The resulting membrane potential, known as the asymmetry potential, is not zero even when analyte concentrations on both sides of the membrane are equal. The membrane's response is typically not selective to a single analyte but proportional to the concentration of all ions in the sample solution capable of interacting at...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Self-heating-induced blocking in nanopores enables neuromorphic ionic computing.

Nature communications·2026

Same author

Pressure Driven Non-monotonic Gating in Tunable Polydimethylsiloxane Nanopores Regulates DNA Translocation.

ACS nano·2026

Same author

Self-Correction of pH-Induced Signal Variations in Methylene Blue-Labeled Aptamer Electrochemical Biosensors: Wearable Cortisol Detection in Sweat.

ACS sensors·2026

Same author

Integration of continuous microfluidic electrokinetic bioparticle preconcentration with programmable extraction into a discrete microfluidic platform.

Lab on a chip·2026

Same author

Probing Ionic Vibrational Dynamics via Terahertz Fluctuations in Nanopore Ionic Current.

The journal of physical chemistry. B·2025

Same author

Toward an ion-based large-scale integrated circuit: design, simulation, and integration.

Communications engineering·2025

Search research articles

Related Experiment Video

Updated: Jul 20, 2025

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

Logic gating of low-abundance molecules using polyelectrolyte-based diodes.

Barak Sabbagh¹, Zhenyu Zhang^2,3, Gilad Yossifon^1,3

¹Faculty of Mechanical Engineering, Technion - Israel Institute of Technology, Israel.

Faraday Discussions

|August 2, 2023

Summary

Researchers developed ionic diodes from oppositely charged polyelectrolytes to control low-abundance molecules. These diodes enable basic Boolean operations, paving the way for on-chip ionic computation and integrated circuits.

More Related Videos

Nanofabrication of Gate-defined GaAs/AlGaAs Lateral Quantum Dots

Nanofabrication of Gate-defined GaAs/AlGaAs Lateral Quantum Dots

Published on: November 1, 2013

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping

Published on: June 3, 2015

Related Experiment Videos

Last Updated: Jul 20, 2025

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Plasmid-derived DNA Strand Displacement Gates for Implementing Chemical Reaction Networks

Published on: November 25, 2015

Nanofabrication of Gate-defined GaAs/AlGaAs Lateral Quantum Dots

Nanofabrication of Gate-defined GaAs/AlGaAs Lateral Quantum Dots

Published on: November 1, 2013

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping

Silicon Metal-oxide-semiconductor Quantum Dots for Single-electron Pumping

Published on: June 3, 2015

Area of Science:

Nanotechnology and Materials Science
Bioinspired Engineering
Chemical Engineering

Background:

Biological signaling heavily relies on ions and molecules, driving interest in bioinspired artificial ionic components.
Nanoscale fluidic components offer precise regulation of ion transport through induced ion permselectivity.
Current research focuses on translating fundamental ion transport principles into functional ion-controlled devices.

Purpose of the Study:

To demonstrate the use of ionic diodes as gates for controlling low-abundance molecules.
To realize basic Boolean logic operations using these ionic diodes.
To explore the integration of ionic diodes for on-chip ionic computation.

Main Methods:

Fabrication of ionic diodes using oppositely charged polyelectrolytes.
Characterization of nonlinear current-voltage responses of the ionic diodes.
Investigation of asymmetric ion transport and its effect on low-abundance molecule transport.
Integration of multiple diodes to implement OR logic gates for both voltage and molecule transport.

Main Results:

Ionic diodes exhibited nonlinear current-voltage responses, enabling an ionic OR logic gate.
Asymmetric ion transport through the diode selectively controlled molecule passage, allowing transport only under forward bias.
Integration of diodes successfully implemented OR logic operations with electrical and optical readouts.
Demonstrated electrical and optical output readouts corresponding to low and high logic levels.

Conclusions:

Ionic diodes serve as effective gates for controlling low-abundance molecules.
The development of ionic logic gates opens possibilities for on-chip ionic computation.
Integration of multiple logic gates can lead to complex ionic integrated circuits.