[WHO classification of tumors of hematopoietic and lymphoid tissues, 2022 (5th edition): lymphoid tumors]
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Updated: Jul 20, 2025

Multiplexed Fluorescent Immunohistochemical Staining, Imaging, and Analysis in Histological Samples of Lymphoma
Published on: January 9, 2019
D V Baram1, Z P Asaulenko2,3, I N Spiridonov3
1Russian Research Institute of Hematology and Transfusiology, St. Petersburg, Russia.
Abstract:
The paper discusses changes in the structure of the classification, criteria for the diagnosis of lymphoid neoplasms in the 5th edition of the WHO Classification of Tumors of Hematopoietic and Lymphoid Tissues (2022). Changes are presented regarding new nosological units, renaming and abolition of some previously existing ones. The importance of molecular genetic studies in the isolation of many lymphomas and the need to apply these studies in everyday clinical practice are emphasized. Lymphoid precancerous processes and lymphoid proliferations introduced into the Classification for the first time are considered.
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