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Blood Transfusion01:15

Blood Transfusion

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Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...
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Blood Transfusion and Agglutination02:45

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Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...
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Bone Marrow Sampling and Transplants01:22

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Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
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Blood Typing01:10

Blood Typing

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Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
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Rh Blood Group01:19

Rh Blood Group

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The Rhesus (Rh) antigen is crucial in determining blood groups and ensuring compatibility during blood transfusions.
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Tissue Transplantation01:24

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Tissue transplantation is a significant medical procedure involving the transfer of cells, tissues, or organs from a donor to a recipient, with the primary aim of restoring lost functions. This procedure is crucial in treating a broad spectrum of diseases, including kidney diseases, liver failure, heart disease, and certain types of cancers.
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The biology of tissue transplantation hinges on the Major Histocompatibility Complex (MHC) molecules. These molecules...
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Testing the Accuracy of Administrative Case Definitions to Identify Thalassemia.

Public health reports (Washington, D.C. : 1974)·2026
See all related articles
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Updated: Jul 20, 2025

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload
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Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

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Transfusion management in thalassemia.

Jeanne Boudreaux1

  • 1Aflac Cancer & Blood Disorders Center, Emory University, Atlanta, Georgia, USA.

Annals of the New York Academy of Sciences
|August 2, 2023
PubMed
Summary

This review addresses challenges and recommendations for thalassemia transfusion management. It covers blood safety, special populations, adverse reactions, pathogen reduction technologies, and future research in blood storage and manufacturing.

Keywords:
bloodthalassemiatransfusion

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Area of Science:

  • Hematology
  • Transfusion Medicine
  • Blood Banking

Background:

  • Thalassemia patients require lifelong blood transfusions.
  • Managing transfusions in these patients presents unique challenges.
  • Ensuring blood safety and efficacy is paramount.

Purpose of the Study:

  • To review current transfusion management strategies for thalassemia.
  • To discuss blood safety components and modifications for special populations.
  • To highlight advancements in pathogen reduction and future research.

Main Methods:

  • Literature review of challenges and recommendations in thalassemia transfusion.
  • Analysis of blood safety protocols and product modifications.
  • Overview of emerging technologies for pathogen reduction.
  • Brief description of research in blood storage and manufactured blood.

Main Results:

  • Identified key challenges in thalassemia transfusion management.
  • Outlined recommendations for optimizing transfusion protocols.
  • Described advancements in reducing transfusion-associated risks.
  • Summarized current research directions in blood products.

Conclusions:

  • Effective transfusion management is crucial for thalassemia patients.
  • Continuous improvement in blood safety and technology is essential.
  • Future research holds promise for enhanced blood therapies.