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Updated: Jul 20, 2025

Application of Deep Learning-Based Medical Image Segmentation via Orbital Computed Tomography
Published on: November 30, 2022
EDRL: Entropy-guided disentangled representation learning for unsupervised domain adaptation in semantic
Runze Wang1, Qin Zhou1, Guoyan Zheng1
1Institute of Medical Robotics, School of Biomedical Engineering, Shanghai Jiao Tong University, No. 800, Dongchuan Road, Shanghai, 200240, China.
This study introduces Entropy-guided Disentangled Representation Learning (EDRL) for unsupervised domain adaptation in medical image segmentation, improving robustness to domain shift without target annotations.
Area of Science:
- Medical Imaging
- Computer Vision
- Machine Learning
Background:
- Deep learning models struggle with domain shift in medical imaging.
- Unsupervised domain adaptation (UDA) aims to bridge this gap without target domain annotations.
Purpose of the Study:
- To develop a robust cross-domain segmentation method for medical images.
- To address the challenge of domain shift in deep learning models.
Main Methods:
- Proposed Entropy-guided Disentangled Representation Learning (EDRL) for UDA.
- Integrated image and feature alignment using disentangled representation and adversarial learning.
- Implemented a dynamic feature selection mechanism via soft gating.
Main Results:
- Achieved state-of-the-art results on CT-MR and multi-sequence cardiac MR datasets.
- Demonstrated high performance in cross-domain segmentation tasks (e.g., 84.8% DSC on CT-MR).
Conclusions:
- The EDRL model effectively enhances cross-domain medical image segmentation.
- Experimental results validate the proposed method's efficacy in handling domain shift.
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