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Updated: Jul 20, 2025
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Published on: August 2, 2024
Neurotrophic Keratopathy After Slow Coagulation Transscleral Cyclophotocoagulation
Mohamed S Sayed1,2, Mohamed M Khodeiry1,3, Abdelrahman M Elhusseiny1,4
1Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL.
Purpose:
Decreased corneal sensation and subsequent neurotrophic keratopathy (NK) is an uncommon complication after transscleral cyclophotocoagulation (TSCPC). Post-TSCPC NK has been rarely reported in the literature, predominantly after traditional, "pop technique" continuous-wave TSCPC or micropulse CPC. The authors report the first case series of NK after slow-coagulation TSCPC (SC-TSCPC).
Methods:
This was a respective chart review of patients who developed NK after SC-TSCPC. The collected data included demographic data, type of glaucoma, risk factors for corneal anesthesia in addition to the number of laser spots, and the extent of the treated area.
Results:
Four eyes experienced NK after SC-TSCPC. The median time for the development of NK was 4 weeks. At the final visit, 2 patients had a resolution of NK, 1 had a persistent corneal ulcer, and 1 had worsening NK and corneal perforation.
Conclusions:
NK is a rare but a vision-threatening complication that can develop after SC-TSCPC in patients with risk factors for decreased corneal sensation. Early diagnosis and proper management are crucial to reducing the risk of vision loss and improving the prognosis of these cases.
