Related Experiment Video
Updated: Jul 20, 2025

Occlusion of the Great and Small Saphenous Vein Using Copolymeric Glue Based on N-Butyl Cyanoacrylate and Methacryloxy Sulfolane
Published on: December 9, 2022
Stocking-only versus additional eccentric compression after below-the-knee truncal vein sclerotherapy: A SOVAECS
Kilsoo Yie1, Eun-Hee Jeong1, Eun-Jung Hwang1
1Department of Surgery, College of Medicine, Pusan National University, and Jeju Soo Cardiovascular Center, Jeju, South Korea.
Additional eccentric compression after foam sclerotherapy in the truncal saphenous vein did not show significant clinical benefits over regular compression stockings. Further research is needed to determine optimal compression strategies post-sclerotherapy.
Area of Science:
- Vascular Surgery
- Phlebology
- Minimally Invasive Procedures
Background:
- Foam sclerotherapy is a common treatment for great saphenous vein (GSV) reflux.
- The role of additional eccentric compression following this procedure remains underexplored.
- Optimizing post-sclerotherapy compression is crucial for treatment efficacy and patient outcomes.
Purpose of the Study:
- To evaluate the clinical effects of additional eccentric compression versus regular compression stockings after foam sclerotherapy in the truncal saphenous vein.
- To compare occlusion range, pain levels, and need for repeat procedures between the two compression methods.
- To assess patient satisfaction and complication rates associated with different compression strategies.
Main Methods:
- A prospective, randomized, single-blind, within-person study involving 42 patients (84 limbs) undergoing bilateral GSV therapy.
- Patients received endovenous ablation above the knee and foam sclerotherapy below the knee.
- Bilateral truncal saphenous veins were treated with either regular class II compression stockings (RC group) or additional eccentric compression (AC group) for 24 hours post-procedure.
Main Results:
- Eccentric compression significantly increased subcompression pressure compared to regular stockings (P=.000).
- No statistically significant differences were observed in occlusion range, postoperative pain, need for additional sclerotherapy, or skin pigmentation between the AC and RC groups.
- Patient-reported satisfaction at 24 hours postoperatively was similar between groups (P=.317), and no procedure-related complications were noted within one month.
Conclusions:
- Twenty-four hours of additional eccentric compression offers no discernible clinical advantages over conventional knee-level stockings after truncal vein foam sclerotherapy.
- The choice of compression therapy post-foam sclerotherapy should be individualized and based on comprehensive patient assessment.
- Current evidence does not support routine use of additional eccentric compression solely based on this study's findings.
Related Concept Videos
Varicose Veins II: Diagnostic Studies and Interprofessional Care
Varicose Veins I: Introduction
Venous Thrombosis II: Clinical Manifestations and Diagnostic Studies
Esophageal Varices-II: Clinical Features and Management
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
Esophageal Varices-I: Introduction
Overview of Systemic Veins
The coronary sinus, the heart's principal vein, resides in the coronary sulcus on the heart's posterior aspect. This broad venous channel receives nearly all venous blood from the myocardium, the heart muscle. It is fed by three primary veins: the great cardiac vein, the...

