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The Impact of Multiple Prostate Needle Biopsies on Long-Term Erectile Dysfunction
Khanh N Pham1, Richard B Johnston1, Claudio Jeldres1
1Section of Urology and Renal Transplantation, Virginia Mason, Seattle, Washington.
Urology Practice
|August 4, 2023
Summary
Transrectal ultrasound guided prostate needle biopsy may cause temporary erectile dysfunction, especially with repeat procedures. However, long-term erectile function is not significantly impacted by prostate needle biopsies in aging men.
Area of Science:
- Urology
- Andrology
- Medical Diagnostics
Background:
- The relationship between transrectal ultrasound guided prostate needle biopsy and erectile dysfunction (ED) is not fully understood.
- This study investigates if prostate needle biopsies contribute to the development or worsening of ED.
Purpose of the Study:
- To assess the short-term and long-term impact of transrectal ultrasound guided prostate needle biopsy on erectile function.
- To evaluate the association between multiple prostate biopsies and erectile dysfunction using the IIEF-5 score.
Main Methods:
- 826 men undergoing 10 to 12-core prostate needle biopsy were assessed using the IIEF-5 questionnaire.
- Erectile dysfunction was categorized (any, mild, moderate, severe).
- The impact of repeat biopsies on ED was analyzed.
Main Results:
- 29% of men had undergone one or more biopsies, 20% had two or more.
- Age and prior biopsies were associated with ED on univariate analysis.
- Repeat biopsy within 12 months correlated with worse ED; however, long-term function was not significantly predicted by biopsy history.
Conclusions:
- Prostate needle biopsy may predict transient ED (less than 1 year) in the short term.
- Prostate needle biopsy does not predict long-term erectile dysfunction in aging men.
