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Updated: Jun 21, 2026

Skin Tattooing As A Novel Approach For DNA Vaccine Delivery
Published on: October 18, 2012
[Hipersensibility to red tattoo ink, review of a case]
Bárbara Isamara Rojo-Rodríguez1, Blanca Elena Verazaluce-Rodríguez2, Samira Viridiana Alcalá-Adame3
1Instituto Mexicano del Seguro Social, Unidad de Alta Especialidad Centro Médico Nacional del Bajío, Servicio de Medicina Interna. León, Guanajuato, México.
Introduction:
The hypersensitivity reaction associated with tattoo ink and its management represent a growing challenge, despite having precedents in diagnostic and treatment experience in other reports or case series in recent decades, no one has been found homogeneous offer that is effective and safe. Therefore, a review is presented with what has been described in pathophysiological theories, as well as therapeutic proposals and the response found in related cases that have been reported to date.
Clinical Case:
30-year-old male, with dermatosis located on the right upper extremity, affecting the inner side of the forearm and the outer side of the arm, unilateral, asymmetric, monomorphic in appearance, made up of an artificial macula, caused by red ink (tattoo), with development of papular-like lesions in original trace, pruritic, referred evolution time of one month. Tattoo completion time of 5 and 2 years on the outer side of the right arm and inner side of the ipsilateral forearm, respectively.
Conclusions:
According to antecedents in other reports and case series, including the experience of our patient, there is no proven efficacy with the use of topical immunomodulators, in turn, patients who shows complete improvement until the elimination of the allergen, either from excisional or laser.
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