Extracerebral anaplastic meningioma

Area of Science:

• Neuro-oncology
• Pathology
• Medical Oncology

Background:

• Anaplastic meningioma is a rare, aggressive brain tumor.
• Extracerebral metastases are exceptionally uncommon.
• Standard treatments include surgery, radiotherapy, and temozolomide.

Observation:

• A patient with cerebral anaplastic meningioma developed lung metastases.
• Metastasis occurred 19 years after the initial diagnosis.
• This presentation is highly unusual and challenging to predict.

Findings:

• The case demonstrates the potential for late-onset, extracerebral spread of anaplastic meningioma.
• Diagnosis can be complicated by the long latency period and rarity of metastases.
• Antiangiogenic drugs may offer a potential salvage therapy option.

Implications:

• This case underscores the importance of long-term surveillance for patients with anaplastic meningioma.
• Understanding the metastatic potential is crucial for comprehensive patient management.
• Further research into the mechanisms of late metastasis is warranted.