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Quantitation of Intra-peritoneal Ovarian Cancer Metastasis
Published on: July 18, 2016
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Ovarian Cancer in Iran: National Based Study
Atieh Akbari1, Mehdi Azizmohammad Looha1, Afshin Moradi1
1Cancer Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran.
Iranian Journal of Public Health
|August 8, 2023
Summary
Ovarian cancer is the 8th most common cancer in Iran. Iranian women have better overall survival rates compared to Western countries, with 5-year survival at 55%.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Ovarian cancer (OC) ranks as the 7th most common cancer globally and 8th in Iran.
- Iranian women exhibit an age-standardized incidence rate (ASIR) of 3.9/100,000, with previous studies indicating a 5-year survival rate of approximately 61%.
Purpose of the Study:
- To analyze the incidence and survival rates of ovarian cancer in Iran.
- To compare Iranian OC statistics with global and regional data.
Main Methods:
- Utilized data from the Iran National Cancer Registry spanning 2009-2014.
- Employed Kaplan-Meier survival analysis to assess survival rates across various demographic and pathological factors.
- Statistical significance was determined using a P-value of 0.05 in R and SPSS software.
Main Results:
- The study included 7977 OC cases, with an overall ASIR of 4.10/100,000.
- Five-year and 10-year overall survival rates were 55% and 45%, respectively.
- Epithelial and non-specific OC showed ASIRs greater than 0.5.
Conclusions:
- Ovarian cancer incidence in Iran is lower and survival rates are better compared to East Asia and North America.
- OC incidence in Iran correlates with decreased total fertility and population aging, similar to Eastern Europe.
- The higher survival rates may be influenced by the exclusion of late-stage OC patients from pathology records.
