Multiple myeloma with unusual intracranial manifestations

We report a unique case of meningeal involvement of multiple myeloma in a 49-year-old man. The patient developed weakness late in the course of his disease, and a computed tomographic scan revealed intracranial masses. At postmortem examination these tumors were the predominant extramedullary manifestation of the patient's anaplastic myeloma. To our knowledge this is the first case of intracranial myeloma composed of multiple, discrete masses.