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Updated: Jul 19, 2025

08:26
Luminophore Formation in Various Conformations of Bovine Serum Albumin by Binding of GoldIII
Published on: August 31, 2018
6.9K
Turn-on fluorescence of ruthenium pyrene complexes in response to bovine serum albumin
Saša Opačak1, Margareta Pernar Kovač1, Anamaria Brozovic1
1Ruđer Boškovic Institute, Bijenička cesta 54, HR-10000 Zagreb, Croatia. Srecko.Kirin@irb.hr.
Dalton Transactions (Cambridge, England : 2003)
|August 9, 2023
Abstract:
Two novel pyrene triphenylphosphine ruthenium conjugates act as fluorescent turn-on beacons for serum albumin, being non-fluorescent in aqueous media but exhibiting strong emission upon binding to BSA. The selective cytotoxicity of the compounds against tumour cells is enhanced upon irradiation by UV-light, paving the way for application in photodynamic therapy under two-photon excitation.

