Related Experiment Video
Updated: Jul 2, 2026
08:41
Calvarial Model of Bone Augmentation in Rabbit for Assessment of Bone Growth and Neovascularization in Bone Substitution Materials
Published on: August 13, 2019
8.3K
Marginal bone level change of immediately restored implants with simultaneous guided bone regeneration: A systematic
Xinyan Lin1,2,3,4,5,6,7, Xinbo Yu1,2,3,4,5,6,7, Feng Wang1,2,3,4,5,6,7
1Second Dental Center, Shanghai Ninth People's Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Clinical Implant Dentistry and Related Research
|August 9, 2023
Summary
Immediate implant restoration with guided bone regeneration (GBR) shows promising results. Simultaneous peri-implant gap filling with GBR leads to less marginal bone loss and better soft tissue outcomes compared to grafting dehiscence or fenestration defects.
Area of Science:
- Dental Implantology
- Periodontology
- Regenerative Dentistry
Background:
- Immediate implant restoration combined with guided bone regeneration (GBR) is a technique used to address bone defects during implant placement.
- Assessing the clinical outcomes of this combined approach is crucial for optimizing treatment predictability.
Approach:
- A systematic review and meta-analysis were planned, but a meta-analysis was not feasible due to the heterogeneity of studies.
- Searches were conducted in major databases (PubMed/MEDLINE, EMBASE, CENTRAL) for studies with at least 12 months follow-up.
- Primary outcome was marginal bone level change (MBLc); secondary outcomes included soft tissue parameters and implant survival rate (ISR).
Key Points:
- Twenty-five studies involving 692 implants were analyzed.
- For peri-implant gap filling, weighted mean MBLc was -0.73 ± 1.52 mm, with an ISR of 98.99%.
- For gap with dehiscence/fenestration augmentation, mean MBLc was -1.19 ± 0.26 mm, with an ISR of 97.25%.
Conclusions:
- Immediate restoration with simultaneous GBR and peri-implant gap filling demonstrates favorable marginal bone levels and soft tissue outcomes.
- Implants with gap filling showed a higher implant survival rate.
- Further research is needed to establish the role of immediate provisional prostheses in conjunction with simultaneous bone augmentation.
