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Caution regarding the specificities of pan-cancer microbial structure

Abraham Gihawi1, Colin S Cooper1, Daniel S Brewer1,2

  • 1Bob Champion Research & Education Building, Norwich Medical School, University of East Anglia, Norwich NR4 7UQ, UK.

Microbial Genomics
|August 9, 2023
PubMed
Summary

Machine learning can potentially distinguish tumor types by microbial composition, but concerns about data quality and analysis methods raise questions about the reliability of these findings for clinical use.

Keywords:
bacteriacancercontaminationmachine learningmicrobiomeviruses

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Bacterial and archaeal cells exhibit remarkable diversity in shape and structure, critical in their adaptability and functionality. Among bacteria, the most commonly observed shapes include cocci and bacilli. Cocci are spherical and may exist singly or in groupings such as pairs (diplococci), chains (streptococci), clusters (staphylococci), or tetrads. Bacilli, in contrast, are rod-shaped and can also occur as single cells, in pairs, or chains, depending on their environmental and genetic...
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