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Antimalarials are not Effective as Pre-Exposure Prophylaxis for COVID-19: A Retrospective Matched Control Study
Journal of Drugs in Dermatology : JDD
|August 9, 2023
Summary
Antimalarial drugs like hydroxychloroquine were investigated for preventing SARS-CoV-2 infection. This study found no evidence that these drugs offer effective pre-exposure prophylaxis against COVID-19.
Area of Science:
- Infectious Diseases
- Pharmacology
- Epidemiology
Background:
- The COVID-19 pandemic led to exploring repurposed drugs for prevention and treatment.
- Antimalarials, including hydroxychloroquine and chloroquine, were investigated but their prophylactic role against SARS-CoV-2 remains unclear.
- Limited data exists on the efficacy of antimalarials as pre-exposure prophylaxis for SARS-CoV-2 infection.

