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Updated: Jul 19, 2025

Multimodal Optical Imaging Platform for Studying Cellular Metabolism
Published on: June 6, 2025
Prediction performance and reliability evaluation of three ginsenosides in Panax ginseng using hyperspectral imaging
Youyou Wang1, Siman Wang1, Ruibin Bai2
1State Key Laboratory for Quality Ensurance and Sustainable Use of Dao-di Herbs, National Resource Center for Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, 100700, PR China.
Abstract:
Panax ginseng C. A. Meyer (PG) is a health-promoting food, and its ginsenosides (Rb1, Rg1, Re) content, as the quality indicator, is affected by the planting modes (garden or forest ginsengs) and years. Effective prediction of this content remains to be investigated. In this study, hyperspectral (HSI) combined with ensemble model (CGRU-GPR) including the convolutional neural network (CNN), gate recurrent unit (GRU), and Gaussian process regression (GPR) realized a comprehensive evaluation of the prediction performance and predictive uncertainty. With effective wavelengths, the proposed CGRU-GPR model improved operation efficiency and obtained satisfactory prediction results with relative percent deviation (RPD) values all higher than 2.70 in three ginsenosides. Meanwhile, the interval prediction with a high prediction interval coverage probability (PICP) of 0.97 - 1.0 and a low mean width percentage (MWP) of 0.7 - 1.66 indicated a low prediction uncertainty. This study provides a rapid and reliable method for predicting ginsenosides contents in PG.
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