Targeted mRNA demethylation in Arabidopsis using plant m6A editor

Ruiqiu Fang1, Xiaolong Chen2, Jie Shen3

  • 1Institute of Maize and Featured Upland Crops, Zhejiang Academy of Agricultural Sciences, Dongyang, 322100, Zhejiang, China. fangruiqiu2013@163.com.

Plant Methods
|August 9, 2023
PubMed
Abstract

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RNA Editing

RNA editing is a post-transcriptional modification where a precursor mRNA (pre-mRNA) nucleotide sequence is changed by base insertion, deletion, or modification. The extent of RNA editing varies from a few hundred bases, in mitochondrial DNA of trypanosomes, to a just single base, in nuclear genes of mammals. Even a single base change in the pre-mRNA can convert a codon for one amino acid into the codon for another amino acid or a stop codon. This type of re-coding can significantly affect the...
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