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Related Experiment Video

Updated: Jul 24, 2026

Use of Magnetic Resonance Imaging and Biopsy Data to Guide Sampling Procedures for Prostate Cancer Biobanking
05:49

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Published on: October 10, 2019

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Prostate biopsy approach and complication rates.

Kinga Mate1,2, Saleh Nedjim3, Simon Bellucci4

  • 1Department of Urology, Péterfy Sándor Utcai Hospital-Clinic and Trauma Centre, Budapest 1076, Hungary.

Oncology Letters
|August 10, 2023
PubMed
Summary

Magnetic resonance imaging (MRI)-guided prostate biopsies may increase early side effects like hematuria, but do not significantly raise late or infectious complications compared to standard biopsies. Transrectal biopsies showed a higher hospitalization rate for sepsis than transperineal approaches.

Keywords:
MRI-guidedcomplicationshematospermiahematuriainfectionsprostate biopsyrectal bleedingsepsistransperinealtransrectalurinary retention

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Area of Science:

  • Urology
  • Oncology
  • Medical Imaging

Background:

  • Prostate biopsy is crucial for diagnosing prostate cancer.
  • MRI-guided biopsies aim to improve detection of clinically significant prostate cancer.
  • Complication rates of different biopsy techniques require comparison.

Purpose of the Study:

  • To compare complications between standard transrectal ultrasound-guided (TRUS) biopsies and MRI-guided plus standard TRUS biopsies.
  • To assess the impact of core number on complication rates.
  • To compare TRUS biopsy complications with literature data on transperineal biopsies.

Main Methods:

  • Prospective study of 84 patients undergoing TRUS biopsies (April-June 2022).
  • Patients were divided into standard biopsy only or standard plus targeted (MRI-guided) groups.
  • Complications were monitored for early and late side effects, including hospitalization.

Main Results:

  • 58.3% of patients had targeted plus standard biopsies; 41.7% had standard only.
  • Early side effects (hematuria, hematospermia) were significantly higher in the targeted plus standard group (63.1% vs. 28.6% late side effects).
  • Hospitalization rate for post-biopsy complications was 3.6%; TRUS sepsis admission rate was 2.29% compared to 0-1% for transperineal biopsies.

Conclusions:

  • Targeted plus standard MRI-guided prostate biopsies increase early side effects but not late or infectious complications compared to standard TRUS biopsies.
  • The transrectal approach showed a higher hospitalization rate for sepsis than transperineal biopsies.
  • Further research is needed on hospitalization complications for both transrectal and transperineal biopsies.