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Comparing Cognitive Functions in Patients with Schizophrenia and Methamphetamine-Induced Psychosis with Healthy
Mahin Eslami Shahrbabaki1, Delaram Barfehie2, Shahrzad Mazhari1
1Neuroscience Research Center and Institute of Neuropharmacology, Psychiatry Department, Afzalipour School of Medicine, Kerman University of Medical Sciences, Kerman, Iran.
Addiction & Health
|August 10, 2023
Summary
Cognitive impairments in schizophrenia and methamphetamine-induced psychosis (MIP) patients show similarities but differ in specific domains. Schizophrenia patients exhibited worse verbal fluency, memory, and processing speed than MIP patients.
Area of Science:
- Neuroscience
- Psychiatry
- Cognitive Psychology
Background:
- Schizophrenia and methamphetamine-induced psychosis (MIP) share overlapping symptoms, including cognitive deficits.
- Understanding the nuances of cognitive dysfunction in these conditions is crucial for effective treatment.
Purpose of the Study:
- To compare cognitive functioning between patients with schizophrenia and MIP.
- To identify similarities and differences in cognitive performance using standardized assessments.
Main Methods:
- The study included 30 patients with MIP, 30 with schizophrenia, and 30 healthy controls.
- Participants completed the Brief Assessment of Cognition in Schizophrenia (BACS) and the Schizophrenia Cognition Rating Scale (SCoRS).
Main Results:
- Both patient groups showed poorer performance on BACS cognitive domains compared to healthy controls.
- Schizophrenia patients performed worse than MIP patients in verbal fluency, verbal memory, and information processing speed.
- Similarities were observed in executive function, working memory, and motor speed between schizophrenia and MIP patients.
Conclusions:
- Cognitive dysfunctions are largely similar between MIP and schizophrenia.
- Key differences emerge in cognitive functions associated with prefrontal and temporal lobe activity.
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